Internal Medicine

Download Oxford handbook of reproductive medicine and family planning by Enda McVeigh, John Guillebaud, Roy Homburg PDF

By Enda McVeigh, John Guillebaud, Roy Homburg

The Oxford guide of Reproductive medication and relations making plans, moment variation offers crucial useful details within the care of the adolescent and reproductive age women and men. Evidence-based and concise, this guide is the must-have source for all practitioners, trainees, and scholars in sexual and reproductive healthcare. absolutely up-to-date for the second one version, this instruction manual now contains  Read more...

Show description

Read or Download Oxford handbook of reproductive medicine and family planning PDF

Best internal medicine books

Vital Lung Function (Vital Guides)

This ebook includes crucial info when you are thinking about breathing care. it's a terrific reference for expert nurses, perform nurses, GPs, and all these healthcare pros who desire a operating wisdom of lung functionality checking out.

The Confinement of the Insane: International Perspectives, 1800-1965

This choice of essays explores the improvement of the lunatic asylum, and the idea that of confinement for these thought of insane, in several nationwide contexts over the 19th and 20th centuries. prime students within the box of clinical historical past have contributed broad fundamental examine via person case reports within the context of the criminal, social, financial, and political events of 13 varied nations.

Short Cases in Clinical Medicine

A worthy studying guide for undergraduates and PG scholars getting ready for FCPS, MD, MRCP, FRACP or the other similar examination in inner drugs.

Oxford handbook of dialysis

The Oxford guide of Dialysis is a finished and useful advisor to all elements of dialysis, the administration of sufferers with finish degree kidney ailment, and all its problems. The fourth version has been thoroughly up-to-date, and covers all elements of dialysis from haemodialysis suggestions and haemodiafitration, to the clinical, nursing and psychosocial features of dealing with sufferers with finish level kidney failure.

Additional resources for Oxford handbook of reproductive medicine and family planning

Sample text

17-hydroxy-progesterone if family history of congenital adrenal hyperplasia. If overweight or frankly obese • Body mass index (BMI), waist circumference, blood pressure. • Fasting glucose and insulin. • SHBG and fasting lipid profile. • Oral glucose challenge test. 47 48 CHAPTER 5 Polycystic ovary syndrome Prevalence • PCOS is the most common female endocrinopathy, affecting 5–10% of women in their reproductive years. • PCOS is associated with 75% of all anovulatory disorders causing infertility.

ACTH receptors in the plasma membrane activate adenylate cyclase with production of the second messenger, cAMP. The effect of ACTH on the production of cortisol is particularly important, with the result that a classic feedback loop is prominent in regulating the circulating levels of corticotrophin-releasing hormone (CRH), ACTH, and cortisol. Mineralocorticoid secretion from the zona glomerulosa is stimulated by an entirely different mechanism. 1 Peptide hormones and associated steroid hormones Peptide hormone Steroid hormone Luteinizing hormone (LH) Progesterone and testosterone Adrenocorticotrophic hormone (ACTH) Cortisol Follicle-stimulating hormone (FSH) Oestradiol Angiotensin II/III Aldosterone STEROID HORMONE BIOSYNTHESIS REACTIONS 17 B 3A C D Cholesterol 5 6 HO Zona glomerulosa Zona fasciculata Zona reticularis P450ssc P450ssc P450ssc Pregnenolone Pregnenolone Pregnenolone 3␤-DH ⌬4,5-isomerase P450c17 3␤-DH ⌬4,5-isomerase 17-OH pregnenolone Progesterone 17-OH pregnenolone P450c21 3␤-DH ⌬4,5-isomerase 11-deoxycorticosterone Corticosterone P450c21 11-deoxycorticosterone aldosterone 11-deoxycortisol P450c11 Dehydroepiandrosterone (DHEA) synthase P450c11 CH2OH CH2OH H3C C O OH HO H3C H3C Cortisol O C O HO H 3C Sulphotransferase 3␤-DH ⌬4,5-isomerase DHEA-S CH2OH CC O O O O 17,20 lyase P450c11 P450c21 17-OH progesterone HO H3C P450c17 Progesterone Corticosterone Aldosterone H3 C O H3 C O Androstenedione Fig.

Steroid metabolism is therefore important not only for the production of these hormones, but also for the regulation of their cellular and physiological actions. INTRODUCTION Cholestrerol CH3 CH CH3 CH3 HO Fig. 1 Structure of cholesterol. CH2 CH2 CH2 CH3 CH CH3 19 20 CHAPTER 2 Steroid hormones Steroid hormone biosynthesis reactions The particular steroid hormone class synthesized by a given cell type depends upon its complement of peptide hormone receptors, its response to peptide hormone stimulation, and its genetically expressed complement of enzymes.

Download PDF sample

Rated 4.20 of 5 – based on 16 votes