By Parveen Kumar CBE BSc MD DM (HC) FRCP FRCP(Edin), Michael L Clark MD FRCP
The 9th variation of this best-selling textbook of medical medication builds even additional on its bold, prize-winning formulation of excellence, comprehensiveness and accessibility.
‘This e-book is wonderful in its breadth and ease-of-use. It nonetheless continues to be the "gold standard", thorough consultant to medical medication its forefathers were.’
BMA clinical ebook Awards judges.
New to this edition:
- 2 new chapters: international healthiness and Women’s Health.
- 25 new authors.
- New on-line editor, Adam Feather, with a group of younger medical professionals to reinforce the ebook which accompanies the print booklet with medical information, key studying issues, drug counsel, studying demanding situations, case stories and MCQs.
- Full textual content remodel to incorporate:
New procedure evaluation diagrams for scientific chapters.
New colored headings to assist establish content material with regards to sickness, administration, investigations and so forth.
New icons to help textual content navigation.
11 new participants and a brand new co-editor, Senaka Rajapakse, of the overseas Advisory Board.
Edited by means of Kumar and Clark, clinicians and educators of world-renowned expertise.
Authors contain specialists on the most sensible in their fields, paired with more youthful medical professionals in the direction of the examination event, to make sure authority and relevance.
Enhanced ebook accompanies the print ebook, for ease of transportation and use at the move.
International Advisory Board, led via Professor Janaka de Silva and Professor Senaka Rajapakse, delivering counsel for international insurance from around the world.
Contributions to the booklet by way of individuals of the foreign Advisory Board to enlarge components of scientific significance of their elements of the world
2 new chapters
- Women’s health
- Global health
25 new younger advisor authors teamed with clinicians on the most sensible in their profession, to make sure the textual content is obtainable for college kids and trainees.
A new position of on-line Editor. Adam Feather and his workforce of younger medical professionals, have created (in the ebook) a number of embedded gains together with: bankruptcy summaries, key-point bins, self-assessment, most sensible counsel, additional content material (videos and pictures) and extra… they've got occupied with permitting extra green freshmen to interpret the aspect, navigate the content material successfully and get the main from the textual content.
New co-editor for the foreign Advisory Board, Professor Senaka Rajapakse from the college of Colombo.
11 new participants of the overseas Advisory Board.
9 new on-line foreign articles, together with:
- Crimean Congo Hemorrhagic Fever
- Visceral Leishmaniasis
Full textual content re-design
- New diagrammatic anatomy and body structure overviews firstly of medical platforms chapters
- Coloured headings to aid distinguish sciences, techniques, etc.
- New icons to assist textual content navigation
- Divided into 3 sections for better ease of navigation:
- Good clinical Practice
- Clinical Sciences
- Clinical Practice
Bigger chapters unbundled into smaller chapters for ease of access.
- Clinical Pharmacy now cut loose Poisoning
- STIs and HIV now become independent from Infectious Disease
- Biliary Tract and Pancreatic sickness now break away Liver
- Rheumatic sickness now break away Bone Disease
- Lipid and Metabolic ailment now break away Diabetes Mellitus
Coming quickly: Semantic zoom - an internet textual content summarising software with a view to supply levels of the book’s content material in reducing degrees of element in accordance with your want: from the complete textual content to the naked necessities. retain checking your registered booklet for updates!
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Additional info for Kumar & Clark's clinical medicine
666). Free radicals A free radical is any atom or molecule which contains one or more unpaired electrons, making it more reactive than the native species. The major free radical species produced in the human body are the hydroxyl radical (OH), the superoxide radical (O2-) and nitric oxide (NO). Free radicals have been implicated in a large number of human diseases. The hydroxyl radical is by far the most reactive species but the others can generate more reactive species as breakdown products. When a free radical reacts with a non-radical a chain reaction ensues which results in direct tissue damage by membrane lipid peroxidation.
G. T cell receptor). ■ The function of these membrane receptors is to initiate a secondary message that ultimately results in activation of a specific enzyme or a DNA-binding protein. This may involve CYTOPLASM This is the fluid component inside the cell membrane and contains many specialized organelles (see Fig. 1). It contains a scaffolding or cytoskeleton that regulates the passage and direction in which the interior solutes and storage granules flow. The cytoplasm contains: ■ Endoplasmic reticulum (ER).
Edinburgh: Churchill Livingstone, 2004. Silverman J, Kurtz Z, Draper J. The Calgary–Cambridge guide: a guide to the medical interview. In: Skills for Communicating with Patients, 2nd edn. Abingdon: Radcliffe Medical Press, 2005. www. html 1 14 Ethics and communication K – Knowledge S – Strategy and summary If the patient wishes to know: Patients who have a clear plan for the next and future steps are less likely to feel anxious and uncertain. The clinician must ensure that: ■ ■ FURTHER READING Baile WF, Lenzi R, Kudelka AP et al.