By J. Larry Jameson, Joseph Loscalzo
The authority of Harrison's in a convenient, full-color paperback dedicated completely to Nephrology and Acid-Base issues A Doody's middle identify for 2011! four big name DOODY'S assessment! "In the Harrison's culture, this booklet integrates pathophysiology with medical administration whereas outlining discoveries in genetics and molecular biology. It comprises a few vital chapters that aren't present in related books: one on model of the kidney to renal harm (including components and mechanisms of renal affliction development) and one on hyperuricemia and gout. The introductory bankruptcy at the easy biology of the kidney, overlaying renal improvement, functionality, and body structure, is particularly good written. This publication meets the predicted Harrison's criteria and examining it's a fulfilling experience."--Doody's assessment carrier that includes the chapters on Nephrology and Acid-Base issues that seem within the landmark Harrison's ideas of inner drugs, 17e, this compact scientific better half promises all of the newest wisdom within the box, subsidized via the medical rigor and reliability that experience outlined Harrison's. you will find insurance that displays the services of popular editors and participants -- offered in a carry-anywhere structure that makes it perfect for the school room, the wards, or the purpose of care. With its ease of use, fundamental diagnosis-speeding directions, and acclaimed state of the art ideas, Harrison's Nephrology and Acid Base problems is a needs to for college kids and clinicians alike. Harrison's Nephrology and Acid-Base problems can provide: present, entire insurance of all significant renal-related displays and illnesses, in addition to acid-base and electrolyte issues sixty three high-yield self-assessment Q&A for examination and board evaluate drawn from Harrison's rules of inner drugs Self-Assessment and Board evaluation, 17e A well timed specialise in the impression of medical advances, with a glance at how genetics and molecular biology are reworking the sphere New diagnostic and therapy options in accordance with proof from fresh scientific reports Integration of pathophysiology with scientific administration issues in all the disease-oriented chapters invaluable content material in print shape from the acclaimed Harrison's DVD beneficial appendix that highlights laboratory values of scientific value The Harrison’s distinctiveness sequence is written by way of an identical world-renowned writer staff who introduced you Harrison’s rules of inner medication, 17e: Anthony S. Fauci, MD; Eugene Braunwald, MD; Dennis L. Kasper, MD; Stephen L. Hauser, MD; Dan L. Longo, MD; J. Larry Jameson, MD, PhD; Joseph Loscalzo, MD, PhD
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Extra resources for Harrison's Nephrology and Acid-Base Disorders
22 ■ Abnormalities of the Urine . . . . . . . . . . . . . . 27 Proteinuria . . . . . . . . . . . . . . . . . . . . 27 Hematuria, Pyuria, and Casts . . . . . . . . . . . . . 29 ■ Abnormalities of Urine Volume . . . . . . . . . . . . 30 Polyuria . . . . . . . . . . . . . . . . . . . . . 30 ■ Further Readings . . . . . . . . . . . . . . . . . 31 Normal kidney functions occur through numerous cellular processes to maintain body homeostasis.
Chronically, this injury leads to intimal proliferation, the so-called onion-skinning appearance (B). ) FIGURE 4-24 Acute tubular necrosis. There is extensive ﬂattening of the tubular epithelium and loss of the brush border, with mild interstitial edema. ) 39 CHAPTER 4 A B eosinophils (B) when caused by a drug hypersensitivity reaction. ) A FIGURE 4-27 Sarcoidosis. There is chronic interstitial nephritis with numerous, conﬂuent, non-necrotizing granulomas. The glomeruli are unremarkable, but there is moderate tubular interstitial ﬁbrosis.
41 Key diagnostic features of selected diseases in renal biopsy and urinalysis are illustrated, with light, immunoﬂuorescence, A and electron microscopic images. Common urinalysis ﬁndings are also documented. B FIGURE 4-1 Minimal change disease. In minimal change disease, light microscopy is unremarkable (A), while electron microscopy reveals podocyte injury evidenced by complete foot process effacement (B). ) FIGURE 4-2 Focal segmental glomerulosclerosis.