Internal Medicine

Download Aquaporins by Stefan Hohmann PDF

By Stefan Hohmann

Aquaporins summarizes the current wisdom during this increasing box of analysis, beginning with the structural research of water channel proteins. next chapters start with mammalian aquaporins, reading body structure and pathophysiology, research of knock-out version animals, and the rules of aquaporin functionality. additionally lined is the distribution and rules of aquaporins in crops and the functionality of water and glycerol channels in microbial structures. Key positive aspects* finished remedy of a topical examine box* Authored through international leaders within the box* Covers structural biology and body structure* Covers varied experimental and organic structures* Chapters on plant and microbial structures* large therapy of mammalian body structure and pathophysiology* Structural research excellently illustrated

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Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum. J. Cell Biol. 125, 803–815. Smith, B. , and Agre, P. (1991). Erythrocyte Mr 28,000 transmembrane protein exists as a multisubunit oligomer similar to channel proteins. J. Biol. Chem. 266, 6407–6415. Smith, B. , Raben, D. , Zeidel, M. , and Agre, P. (1993). Concurrent expression of erythroid and renal aquaporin CHIP and appearance of water channel activity in perinatal rats. J. Clin. Invest. 92, 2035–2041.

Kim, J. , and Schrier, R. W. (1998). Upregulation of aquaporin 2 water channel expression in pregnant rats. J. Clin. Invest. 101, 1076–1083. Opperman, C. , Taylor, C. , and Conkling, M. A. (1994). Root-knot nematode-directed expression of a plant root-specific gene. Science 263, 221–223. , Kishore, B. , and Knepper, M. A. (1997). A selective pathway mediates NaCl induced water flux across descending vasa recta. Am. J. Physiol. Renal 272, F587– F596. Preston, G. , and Agre, P. (1991). Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: Member of an ancient channel family.

J. Bacteriol. 144, 274–278. 34 Peter Agre et al. Heymann, J. , and Engel, A. (1998). Progress on the structure and function of aquaporin-1. J. Struct. Biol. 121, 191–206. , Nasrallah, J. , and Nasrallah, M. E. (1997). An aquaporin-like gene required for the Brassica self-incompatibility response. Science 276, 1564–1566. , and Marumo, F. (1994). Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells.

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