By American College of Chest Physicians
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Extra resources for ACCP pulmonary medicine board review
However, pregnant women used a greater number of therapies and received more intense monitoring of their health. Moss RB, Rodman D, Spencer LT, et al. Repeated adeno-associated virus serotype 2 aerosol-mediated CF trans-membrane regulator gene transfer to the lungs of patients with CF: a multicenter, double-blind, placebocontrolled trial. Chest 2004; 125:509–521 This eight-center CF gene therapy study determined the safety of repeated doses of aerosolized adeno-associated vector containing CFTR complementary DNA.
33). Forty percent of patients with a diagnosis of cancer within 1 year of hospitalization for VTE had distant metastases at the time of the diagnosis of cancer. The authors conclude that an aggressive search for hidden cancer in patients presenting with VTE is not warranted. Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism.
Patients who experience a major central thromboembolic event, or have significant hemodynamic compromise on presentation, a documented thrombophilia, or persistent abnormalities seen on lung perfusion studies on follow-up may need to be monitored more closely. Ventilation/perfusion . (V/Q ) scanning is the screening investigation of choice because many chest radiologists are not familiar with the distinguishing features of CTEPH seen on CT angiography. Patients who are surgical candidates should be referred to a specialty center for the consideration of pulmonary endarterectomy.