Internal Medicine

Download A comprehensive guide to the hazardous properties of by Pradyot Patnaik PDF

By Pradyot Patnaik

The definitive advisor to the detrimental homes of chemical compounds

Correlating chemical constitution with toxicity to people and the surroundings, and the chemical constitution of compounds to their damaging homes, A accomplished consultant to the dangerous homes of chemicals, 3rd Edition permits clients to evaluate the toxicity of a substance even if no experimental information exists. hence, it bridges the space among damaging fabrics and chemistry. broadly up to date and accelerated, this reference:

  • Examines organics, metals and inorganics, commercial solvents, universal gases, particulates, explosives, and radioactive components, protecting every little thing from toxicity and carcinogenicity to flammability and explosive reactivity to dealing with and disposal practices
  • Arranges damaging chemicals in response to their chemical buildings and useful teams for simple reference
  • Includes up-to-date info at the poisonous, flammable, and explosive houses of chemical substances
  • Covers extra metals within the chapters on poisonous and reactive metals
  • Updates the brink publicity limits within the office air for a couple of substances
  • Features the most recent info on commercial solvents and poisonous and flammable gases
  • Includes a variety of tables, formulation, and a word list for fast reference

since it presents details that allows people with a chemistry history to accomplish tests with no earlier info, this entire reference appeals to chemists, chemical engineers, toxicologists, and forensic scientists, in addition to commercial hygienists, occupational physicians, Hazmat execs, and others in similar fields.

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Additional resources for A comprehensive guide to the hazardous properties of chemical substances

Example text

Acetyl conjugation: ⎤ Primary aliphatic amine ⎥ acetyl ⎥ Primary aromatic ⎥ acetylation ! ) 12. Amino acid conjugation: ⎤ ˛-amino Aromatic acids, for carboxylic ⎥ example, ⎥ glycine, acids ⎥ glutamine amino acid ⎥ ! conjugates Arylacrylic ⎥ ⎥ acids ⎥ ⎦ Arylacetic acids 13. Sulfate conjugation: ⎤ Aliphatic alcohols ⎥ sulfate sulfate ⎥ Phenols ⎥ ! C TOXIC PROPERTIES OF CHEMICALS — OVERVIEW Of more than 10 million compounds that have been isolated or synthesized, toxicity data have been documented for a little more than 100,000 substances — only a small fraction.

Phytotoxic Poisonous to plants, inhibiting plant growth. Pulmonary Pertaining to the lungs. Pulmonary edema Excess fluid in the lungs, caused by irritants that injure the pulmonary epithelium. Such conditions can affect oxygen uptake, causing death. Receptor Binding site that has a high affinity for a particular ligand. Receptors interact with biologically endogenous ligands, facilitating intracellular communication. Many chemicals interact with receptors, producing a variety of toxic effects. Renal Pertaining to the kidney.

Hydrogen cyanide and metal cyanides, especially those of alkali metals, are extremely acute poisons. The cyanide ion is an inhibitor of cytochrome oxidase, blocking 23 cellular respiration. Many metal ions, including arsenic, cadmium, lead, mercury, manganese, barium, and selenium, are highly toxic to humans. Metals such as antimony, cobalt, nickel, zinc, molybdenum, silver, copper (dust), and aluminum exhibit either low acute poisoning or chronic toxicity. The toxicity of metals also varies widely.

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